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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 20.3
Human Site: S584 Identified Species: 29.78
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S584 I S S I D S T S S Y F N H Y R
Chimpanzee Pan troglodytes XP_526380 1125 128795 R644 L K G I G K P R K F S K F S L
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S584 I S S I E S T S S C F N H Y R
Dog Lupus familis XP_545291 1075 123911 S585 I S S I G S A S S Y C N H C R
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S584 I S S I D S T S S Y F S H C R
Rat Rattus norvegicus P70496 1074 123795 S584 I S S V D S A S S Y F N H Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 S583 V S S I D S E S S C C N P F R
Frog Xenopus laevis NP_001129642 1039 119219 K559 R G L G K S K K F A K F S L Y
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 R541 P K L K G I G R T R K T R F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 K830 G I A L E G M K L N T P E M E
Honey Bee Apis mellifera XP_001121004 1135 129725 D612 M Q P L E K S D T M K C D T P
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 A893 A K S G M D F A S A A E K Y K
Sea Urchin Strong. purpuratus XP_784455 790 90080 P374 L G K D Y Y N P I F K D V V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 V552 P R M P W H D V H C A L W G P
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 S769 D S L W T K H S M L N L H P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 6.6 86.6 73.3 N.A. 86.6 86.6 N.A. 0 60 6.6 0 N.A. 0 0 20 0
P-Site Similarity: 100 20 93.3 73.3 N.A. 93.3 93.3 N.A. 0 73.3 6.6 13.3 N.A. 20 33.3 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 13 7 0 13 13 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 13 7 0 13 0 % C
% Asp: 7 0 0 7 25 7 7 7 0 0 0 7 7 0 0 % D
% Glu: 0 0 0 0 19 0 7 0 0 0 0 7 7 0 7 % E
% Phe: 0 0 0 0 0 0 7 0 7 13 25 7 7 13 0 % F
% Gly: 7 13 7 13 19 7 7 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 7 7 0 7 0 0 0 38 0 0 % H
% Ile: 32 7 0 38 0 7 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 19 7 7 7 19 7 13 7 0 25 7 7 0 7 % K
% Leu: 13 0 19 13 0 0 0 0 7 7 0 13 0 7 7 % L
% Met: 7 0 7 0 7 0 7 0 7 7 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 7 7 32 0 0 7 % N
% Pro: 13 0 7 7 0 0 7 7 0 0 0 7 7 7 13 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 7 7 0 0 0 0 0 13 0 7 0 0 7 0 38 % R
% Ser: 0 44 44 0 0 44 7 44 44 0 7 7 7 7 7 % S
% Thr: 0 0 0 0 7 0 19 0 13 0 7 7 0 7 0 % T
% Val: 7 0 0 7 0 0 0 7 0 0 0 0 7 7 0 % V
% Trp: 0 0 0 7 7 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 7 7 0 0 0 25 0 0 0 25 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _